Inhibition of HCN1 currents by norquetiapine, an active metabolite of the atypical anti-psychotic drug quetiapine.

Pair-wised assessment of NQTP on HCN2 leads to a −3.2 ± 1.7 mV change in the voltage-dependence of activation, however, this did not reach statistical significance (P = 0.09).

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