Does the guide sheath outperform the non-guide sheath method in endobronchial ultrasound-guided biopsy of peripheral pulmonary lesions?-a meta-analysis.

When subgroup analysis was performed based on the different locations of pulmonary nodules within lung lobes, it was found that when nodules were located in the upper lobe, EBUS-GS exhibited a higher diagnostic rate for PPLs compared to EBUS-nGS, although this difference did not reach statistical significance (OR: 1.29, 95% CI: 0.98–1.69, Z=1.79, P=0.07).

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