Clinical associations of complement-activating collectins, collectin-10, collectin-11 and mannose-binding lectin in preterm neonates.

Intriguingly, the median concentration of CL-11 in cord sera from preterm neonates was exactly the same as in sera from healthy adults (0.32 μg/ml) while CL-10 levels differed markedly: 0.63 μg/ml reported here for babies and 1.87 μg/ml for blood donors ( 16 ), despite highly significant CL-10/CL-11 correlation in both studies (r=0.91 and r=0.741, respectively).

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The difference between median serum MBL in babies born at GA 24-32 and those born at GA 33-37 did not reach statistical significance ( Figure 3A ), nor was there any significant difference in frequency of low (<150 ng/ml) concentrations between those groups: 22/94 (24.5%) vs. 72/354 (20.3%) ( Table 2 ).

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