Exploring the Gene Expression and Plasma Protein Levels of HSP90, HSP60, and GDNF in Multiple Sclerosis Patients and Healthy Controls.

Curr Issues Mol Biol · 2024 · PMC11505768 · PMID 39451573

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0794

boldest claim

The sentences

highly significantp < 0.0001actually significant

The highly significant p -value ( p < 0.0001) reinforces the reliability of this association, making it clear that this relationship is far from coincidental.

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did not reach statistical significancep -value = 0.0794so close (0.05 < p ≤ 0.1)

For GDNF protein concentration, while the median for MS males (0.08585 ng/mL) was higher than for MS females (0.05435 ng/mL), this difference did not reach statistical significance ( p -value = 0.0794).

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a slight trendno p-value reported

Although GDNF gene expression and GDNF protein concentrations showed a slight trend towards higher values in MS females, these differences were not statistically significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.