Genetic Variability in Oxidative Stress, Inflammatory, and Neurodevelopmental Pathways: Impact on the Susceptibility and Course of Spinal Muscular Atrophy.

The threshold for statistical significance was set at 0.05, except for the genetic data, for which the threshold for significance was set at 0.0016 (0.05/31), with p values less than 0.0016 considered to indicate statistical significance and p values between 0.0016 and 0.050 considered nominally significant.

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When the data were compared between MS patients and control individuals, a highly significant difference was found between patients and controls in both the genotypic and allelic frequencies of MIR146A rs2910164 (Labib et al. 2018 ).

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