Unveiling the microRNA landscape in pancreatic ductal adenocarcinoma patients and cancer cell models.

During the progression from the primary tumor cell line (BxPC-3) to the metastatic one (AsPC-1), miR-216a-5p expression decreased ( p < 0.001) but it showed an increasing trend in CSCs models.

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Under the same conditions, we observed an upward trend in miR-125a-5p, miR-324-5p, and miR-216a-5p in the serum of cases, although the difference did not reach statistical significance (Fig. 3 ).

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