Regulating Aggregation-Induced Emission Luminogen for Multimodal Imaging-Navigated Synergistic Therapy Involving Anti-Angiogenesis.

As illustrated in Figure 3 A , the fluorescence signals at the tumor site showed a trend of enhancement after 3 h post‐injection of TS NPs, and the fluorescence intensity at the tumor site gradually increased over time, indicating that TS NPs could effectively accumulate at the tumor site by EPR effect.

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Luminogens with aggregation‐induced emission (AIE) tendency have been recognized as an extraordinarily significant template to afford high‐performance multimodal phototheranostics by virtue of its distinctive capability on subtly regulating the balance between radiative and nonradiative energy dissipations by modulating intramolecular motions.

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