Dapagliflozin mitigates cellular stress and inflammation through PI3K/AKT pathway modulation in cardiomyocytes, aortic endothelial cells, and stem cell-derived β cells.

Cardiovasc Diabetol · 2024 · PMC11520772 · PMID 39472869

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hedged sentences

0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

highly significantp < 0.0001actually significant

1 G and H), we observed a highly significant ( p < 0.0001) reduction in hypertrophy in the pre-stimulated cardiomyocytes.

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did not reach statistical significanceno p-value reported

Although we observed a reduction in TNFα expression upon DAPA treatment (i.e., LPS + DAPA group), this difference did not reach statistical significance.

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