Barely Significant
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Immunohistochemical analysis of tumor budding in stage II colon cancer: exploring zero budding as a prognostic marker.

Virchows Arch · 2024 · PMC11522105 · PMID 38977466

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A tendency toward a beneficial effect of adjuvant chemotherapy has been demonstrated in intermediate and high-grade budding tumors; however, the results did not reach statistical significance [ 10 ].

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