Transcriptome sequencing and Mendelian randomization analysis identified biomarkers related to neutrophil extracellular traps in diabetic retinopathy.

The correlation analysis indicated a highly significant negative correlation between GBP2 and P2RY12 (cor = -0.641, p = 0.002), while a significant positive correlation was observed between GBP2 and PSAP (cor = 0.660, p = 0.002) ( Figure 4D ; Supplementary Table S3 ).

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Especially, this may be the reason that the expression of HOXA1 and CLIC3 did not reach statistical significance.

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