High circulating activin A plasma levels are associated with tumour stage and poor survival in treatment-naive lung squamous cell cancer patients.

Transl Oncol · 2025 · PMC11525229 · PMID 39405924

Europe PMC DOI

hedged sentence

0.0650

closest p · 1.3× alpha

0.0650

boldest claim

The sentences

did not reach statistical significancep = 0.065so close (0.05 < p ≤ 0.1)

3 B), while in advanced stages, a trend towards shorter OS for patients with high ActA plasma levels did not reach statistical significance (median OS 7.33 vs 23.23 months, HR 0.462, 95 % CI 0.186–1.141, p = 0.065, Fig. 3 C).

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