The mutants showed a slight trend towards increased sensitivity to H 2 O 2 compared to WT strains, which was not statistically significant, and no change in sensitivity to CHP compared to WT.
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Candida albicans pathways that protect against organic peroxides and lipid peroxidation.
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While not statistically significant, the glr1Δ/Δ mutant showed a trend of increased levels of ROS accumulation at 60 m of exposure to t-BHP, even though the glr1Δ/Δ mutant was not significantly more sensitive to oxidation in the 48 h halo assay ( Fig 5C ).