An Engineered Self-biomineralized Oncolytic Adenovirus Induces Effective Antitumor Immunity and Synergizes With Immune Checkpoint Blockade.

Although the depletion of NK cells also significantly decreased CD3 + T cells, CD4 + T cells, and CD8 + T cells, these cells still showed a trend toward higher frequencies in oADV-W6-CaP–treated mice than in PBS-treated mice ( Fig. 6E ).

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