The KW/BW ratio was decreased, but it did not reach statistical significance (KW/BW F1 control = 0.0142 ± 0.00168g; paternal LPD = 0.0134 ± 0.00156g, p = 0.13) ( Fig. 4 E).
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Morphometric analysis of the intergenerational effects of protein restriction on nephron endowment in mice.
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At three months, there was a decreasing trend in body weight but no significant difference between LPD and NPD offspring (BW NPD F1 = 45.4 ± 6.67g, n = 12; LPD F1 = 43.3 ± 6.35g, n = 11, p = 0.38, Wilcoxon test) ( Fig. 3 A) in both males and females ( Fig. 3 B).