A significant interaction was identified between the dietary modification trial arm and fat response genetic score for LDL-cholesterol concentration ( P = 0·002), where participants in the control arm showed a trend towards minimal reductions in LDL-cholesterol concentrations at higher fat response genetic scores, while the opposite trend was observed in participants following a low-fat diet ( 125 ) .
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Interaction between genetic risk score and dietary fat intake on lipid-related traits in Brazilian young adults.
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