[ 24 ] observed no significant difference in the average pain levels although the average analgesic requirement was lower in the bupivacaine group (100 mg in 50 cc saline) but did not reach statistical significance.
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Efficacy of High-Volume Low-Concentration Intraperitoneal Bupivacaine Irrigation for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: Bupivacaine Irrigation for Analgesia.
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