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Time-Dependent Comparison of the Structural Variations of Natural Products and Synthetic Compounds.

Int J Mol Sci · 2024 · PMC11547171 · PMID 39519027

2
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an increasing trendno p-value reported
Higher numbers of spiro atoms and bridge head atoms can be seen in NP ring assemblies, and they show an increasing trend.

also in 63,971 other papers

a clear trendno p-value reported
There is a clear trend of decreasing ring assembly uniqueness and novelty in SCs.

also in 19,460 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.