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Genetically modified E. Coli secreting melanin (E.melanin) activates the astrocytic PSAP-GPR37L1 pathway and mitigates the pathogenesis of Parkinson's disease.

J Nanobiotechnology · 2024 · PMC11552183 · PMID 39523310

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Behavioral analysis revealed that Tx14(A) effectively rescued pole test performance, while rotarod test, grip strength test, and wire hang test showed some improvement but did not reach statistical significance yet (Fig. 7 B).

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