Barely Significant
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High CTLA-4 gene expression is an independent good prognosis factor in breast cancer patients, especially in the HER2-enriched subtype.

Cancer Cell Int · 2024 · PMC11552348 · PMID 39523362

3
hedged sentences
0.0720
closest p · 1.4× alpha
0.1200
boldest claim

The sentences

a trend towards significancep = 0.072so close (0.05 < p ≤ 0.1)
A trend towards significance was also observed between PDCD1 (PD1) overexpression and luminal B/HER2-negative and TN/BL tumors (both p = 0.072).

also in 2,760 other papers

a trend toward significancep = 0.096so close (0.05 < p ≤ 0.1)
A trend toward significance was observed between FOXO1 expression and low sTIL density ( p = 0.096), and negative lymph node status ( p = 0.055).

also in 3,729 other papers

did not reach statistical significancep = 0.120not close (p > 0.1)
We performed Kaplan-Meier curves for OS and observed that patients with luminal B/HER2-positive overexpressing CD274 (PDL1) showed higher OS, but the differences did not reach statistical significance ( p = 0.120) (Figure S1 ).

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