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Generating bat primary and immortalised cell-lines from wing biopsies.

Sci Rep · 2024 · PMC11555217 · PMID 39528525

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Interestingly, heat-inactivated SARS-CoV-2 induced a significant activation of NF-κB in R42 cells compared to untreated control, while R49 cells and immortalised cell lines had a more modest increase in TLR activity in response to heat-inactivated SARS-CoV-2 that did not reach statistical significance.

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