Investigating the mechanisms of resveratrol in the treatment of gouty arthritis through the integration of network pharmacology and metabolics.

A P value <0.05 was considered statistically significant, and P<0.01 was considered highly significant. 4.

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The results showed that both in serum samples and ankle joint tissue samples, the blank group and the model group were clearly separated, and there were significant differences between the two groups, reflecting the high reliability of the model established in this study, as shown in ( Figures 7A, B ); when comparing the blank group, model group, and Res treatment group, it can be found that all three groups showed their own clustering and the Res group showed a trend towards normal treatment group, indicating that Res can improve the metabolic deviations in serum and ankle joint tissue samples of model rats, as shown in ( Figures 7C, D ).

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