Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors: Guardians against Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Heart Diseases.

ACS Pharmacol Transl Sci · 2024 · PMC11555527 · PMID 39539254

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26 In acute MI rats, DAPA treatment showed a trend of improvement in both mitochondrial morphology and structure within the infarcted myocardium. 180 Moreover, the study revealed that DAPA raised the total number of mitochondria per cardiomyocyte and increased mitochondrial counts, indicating that the mitochondrial serine/threonine protein phosphat

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