Associations between sex and lifestyle activities with cognitive reserve in mid-life adults with genetic risk for Alzheimer's disease.

Simple slope analyses for APOE4 carrier showed a trend positive relationship for females (β (SE) = 0.16 (0.08), CI -0.002–0.32, p = 0.053), and a significantly negative association (β (SE) = -0.20 (0.10), CI -0.40 – -0.001, p = 0.049) for males (Fig. 4 B), between occupational attainment and episodic and relational memory.

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