Power The number of cases and controls in the discovery sets provided at least 80% power to detect nominally significant (α = 0.05) associations with CAD with OR ranging from 0.4 (MAF = 0.01) to 0.65 (MAF = 0.05) for protective variants and from 1.45 (MAF = 0.05) to 2.2 (MAF = 0.01) for predisposing variants.
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Low-frequency variants in genes involved in glutamic acid metabolism and γ-glutamyl cycle and risk of coronary artery disease in type 2 diabetes.
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