Genetic basis of right and left ventricular heart shape.

GARFIELD reads variants from our GWAS summary statistics using two p -value thresholds: genome-wide significance ( p = 5 × 10 −8 ) and borderline significant ( p = 1 × 10 −6 ) in its analysis.

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Using genes for each PC individually in pathway analysis resulted in nominally significant results for some PCs (Supplementary Data 19 ), therefore we performed a pathway analysis including all 69 candidate genes from across all PCs.

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