Hepatitis B Virus and Hepatitis C Virus Affect Mitochondrial Function Through Different Metabolic Pathways, Explaining Virus-Specific Clinical Features of Chronic Hepatitis.

Consistent with our in vitro findings, in people with chronic hepatitis B there was significantly increased expression of PDK1, PDK2, and PDK3 compared to healthy liver ( Figure 7 A – C ), with a strong trend towards increased expression of LDHA ( P =0.057; Figure 7 D ).

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