Pilot implementation of the revised criteria for staging of Alzheimer's disease by the Alzheimer's Association Workgroup in a tertiary memory clinic.

In contrast, during the late biological stages (from Stage C to Stage D), steep declines were observed in all five cognitive domains, although the decline in the language domain did not reach statistical significance (post hoc p = 0.185; Figure S3 ).

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The vascular burden (V; WMH volume) exhibited an increasing trend with advancing tau‐PET‐based biological staging, despite ongoing debates about the tau‐WMH relationship. 33 , 34 , 35 , 36 , 37 Our initial attempt affirmed the clinical feasibility of the new staging scheme.

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