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Development and validation of a model for early survival prediction following liver transplantation based on donor and recipient characteristics.

Ann Med · 2024 · PMC11571776 · PMID 39351705

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an increasing trendno p-value reported
Our analysis also reveals that donors with fatty liver exhibit significantly higher IL10 levels compared to those without, with IL10 levels showing an increasing trend with the severity of steatosis.

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Regarding the prediction of 2-month and 12-month survival, SA10 (AUC = 0.76, 95%CI = 0.58–0.95; AUC = 0.69, 95%CI = 0.56–0.81, respectively) demonstrated higher predictive performance compared to EAD (AUC = 0.67, 95%CI = 0.52–0.83; AUC = 0.58, 95%CI = 0.46–0.69, respectively), MEAF (AUC = 0.76, 95%CI = 0.63–0.88; AUC = 0.59, 95%CI = 0.46–0.72, respectively), L-GrAFT7 (AUC = 0.70, 95%CI = 0.56–0.84; AUC = 0.59, 95%CI = 0.45–0.73, respectively), and L-GrAFT10 (AUC = 0.71, 95%CI = 0.55–0.88; AUC = 0.65, 95%CI = 0.52–0.78, respectively), although the differences did not reach statistical significance.

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