Cognitive impact and brain structural changes in long COVID patients: a cross-sectional MRI study two years post infection in a cohort from Argentina.

Although only a subset of these regions remained significant after correction for multiple comparisons, the overall pattern of reduction suggests a clear trend, underscoring the importance of studying the long term effects of long COVID to determine whether it may increase the risk of neurodegenerative diseases in the future.

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Notably, TMT-A was the only test in our study with marginally significant differences, suggesting that specific tasks might be more susceptible to impairment in long COVID.

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