A recent study by Barrios et al showed promising effects of oxygen in intermediate–high risk PE but the study was prematurely terminated and did not reach statistical significance. 45 However, it did support the hypothesis that mechanisms of oxygen observed in porcine study are translatable to human patients.
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Supplemental oxygen for pulmonary embolism (SO-PE): study protocol for a mechanistic, randomised, blinded, cross-over study.
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