Barely Significant
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An investigation of the effect of the protein corona on the cellular uptake of nanoliposomes under flow conditions using quartz crystal microgravimetry with dissipation.

Nanoscale Adv · 2024 · PMC11575535 · PMID 39569329

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showed a trendno p-value reported
4,38,44 All NLP groups showed a trend in zeta potential toward −20 mV, confirming the presence of a protein corona on their surface.

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an increasing trendno p-value reported
Prior to protein corona formation, the NTA indicated an average NLP size of approximately 100 nm with an increasing trend in their size after protein corona formation, suggesting that a protein layer was formed around the particles.

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a decreasing trendno p-value reported
These findings suggest that the cell monolayer is less viscoelastic after the attachment of protein corona NLPs, which caused a decreasing trend in the dissipation shift, and that the protein coronation of negatively charged NLPs had the least effect on the cell membrane viscoelasticity.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.