TBK1-associated adapters TANK and AZI2 protect mice against TNF-induced cell death and severe autoinflammatory diseases.

Markers of liver damage, total bilirubin, and AST were increased in Tank / Azi2 DKO / Ripk1 KD/KD mice as compared to control animals, although we noticed a substantial variation between animals, and the differences in AST did not reach statistical significance (Fig. 6i ).

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