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Genetically predicted circulating linoleic acid levels and risk of osteoarthritis: a two-sample mendelian randomization study.

BMC Musculoskelet Disord · 2024 · PMC11577923 · PMID 39563274

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showed a trendno p-value reported
Fortunately, a recent study measuring the fatty acid composition of knee synovial fluid showed a trend toward decreased omega-6 in the synovial fluid of OA patients compared to healthy individuals, which also seems to provide limited support for our conclusions [ 48 ].

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