Co-cultures with TLR7-treated CB-pDCs showed a trend towards enrichment of the cytotoxic mediators granzyme A, granulysin, and soluble FAS whereas untreated CB-pDCs in the co-cultures induced stronger granzyme B and perforin secretion.
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Human CD34<sup>+</sup>-derived plasmacytoid dendritic cells as surrogates for primary pDCs and potential cancer immunotherapy.
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