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Outcomes of dermal substitutes in burns and burn scar reconstruction: A systematic review and meta-analysis.

Wound Repair Regen · 2024 · PMC11584356 · PMID 39435560

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Between 5 and 7 days post‐operative, the graft take was higher in the control group compared to the experimental group (−3.13%; 95% CI [−9.15, 2.90]; I 2 = 59%; p = 0.31), but this difference in result did not reach statistical significance (Figure 3A ). 17 , 20 , 21 , 22 On the contrary, there was a statistically significant difference in re‐epithelialization rate at 4–7 days post‐surgery, with the rate being lower in the experimental group (−7.30%; 95% CI [−13.54, −1.05]; I 2 = 0%; p = 0.02) (Figure 3B ). 17 ,

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In addition, we expected a positive trend towards improved scar quality and a positive trend towards improved clinical scar assessment with the use of dermal substitutes, which was indeed seen in this analysis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.