Unfavorable Prognostic Impact of HER2 2+/FISH-Negativity in Older Patients with HER2-Negative and High-Risk Breast Cancer.

Breast Cancer (Dove Med Press) · 2024 · PMC11586453 · PMID 39588273

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did not reach statistical significanceno p-value reported

However, due to the limitation of sample size, the results of subgroup analysis did not reach statistical significance.

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marginally significantno p-value reported

In both hormone receptor (HR)-positive (Log rank test, P =0.052) and HR-negative (Log rank test, P =0.125) subgroups, HER2 2+/FISH-negativity showed a marginally significant adverse influence on DFS.

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