Barely Significant
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Exploiting the role of CSF NfL, CHIT1, and miR-181b as potential diagnostic and prognostic biomarkers for ALS.

J Neurol · 2024 · PMC11588799 · PMID 39340541

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a negative trendno p-value reported
In the ALS group, there was a significant inverse correlation of age at evaluation with both CSF NFL ( r = – 0.178, p = 0.017) and CSF miR-181b levels ( r = – 0.233, p = 0.030); a negative trend was also observed for CSF CHIT1, albeit without statistical significance (Fig. 3 A–C ).

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