Impulse (hangwire time normalized to body mass) was greater in tideglusib-treated mdx mice than in vehicle-treated mdx mice, though this did not reach statistical significance, which we believe could be due to the high degree of variability that can be observed with this test ( p = 0.09; Fig. 3d ).
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GSK3 inhibition improves skeletal muscle function and whole-body metabolism in male mouse models of Duchenne muscular dystrophy.
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