The Impact of Bone Marrow Involvement on Prognosis in Diffuse Large B-Cell Lymphoma: An 18F-FDG PET/CT Volumetric Segmentation Study.

In the assessment of OS5 in DLBCL patients, our study found that, while the established clinical parameter IPI, along with some of its constituents (stage and WHO), emerged as the sole statistically significant prognostic factor, there was a notable trend towards significance for FDG PET/CT-defined tumor burden parameters.

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This suggests that while FDG PET/CT parameters did not reach statistical significance at the 5-year mark contrary to other reports [ 15 ], they may still hold potential prognostic value, albeit to a lesser degree.

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