Efficacy of Polyphenylene Carboxymethylene (PPCM) Gel at Protecting Type I Interferon Receptors Knockout Mice from Intravaginal Ebola Virus Challenge.

When merging data, regardless of viscosity (n = 20 for both vehicle- and PPCM-treated groups), the number of EBOV positive vaginal swabs (≥10 1.82 PFU/mL) at day 2 was not different, although approaching significance ( p = 0.0536), but it was higher in the vehicle-treated group ( p = 0.019) by day 4 ( Supplementary Table S1 ), supporting the differences in median survival data and thus the role of PPCM in delaying disease.

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