Cumulus cell DNA damage linked to fertilization success in females with an ovulatory dysfunction phenotype.

Although this result did not reach statistical significance (Mann-Whitney test: U = 14.0; n 1 = 3; n 2 = 16; p = 0.288), it suggests a potential association between reduced %TDNA levels and oocyte competence, particularly in cases with a high number of 0 PN oocytes. 4 Discussion This study aimed to investigate the relationship between DNA damage in cumulus cells of females undergoing ICSI and oocyte competence, with a focus on IVF outcomes.

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