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CircHipk3 serves a dual role in macrophage pyroptosis by promoting NLRP3 transcription and inhibition of autophagy to induce abdominal aortic aneurysm formation.

Clin Transl Med · 2024 · PMC11599875 · PMID 39601144

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While there was a trend towards a positive correlation between circHipk3 and CASP1, it did not reach statistical significance (Supporting Information Figure S2A–C ).

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