Even moderate liver fat accumulation below conventional fatty liver cutoffs is linked to multiple metabolomic alterations and gestational dysglycemia in Asian women of reproductive age.

Association of liver fat with incident T2D risk score and glucose AUC and GDM incidence at mid-gestation The prospective multi-metabolite risk score (derived from phenylalanine, non-esterified cholesterol in large HDL and the ratio of cholesteryl ester to total lipid in large VLDL) for incident T2D showed an increasing trend from Low to Moderate to High liver fat groups (Fig. 7 a).

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However, we have also shown a significant trend of increasing mid-gestational continuous glucose AUC values from Low to Moderate to High liver fat groups.

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