Exposure to brominated flame retardants <i>in utero</i> and through lactation delays the development of DMBA-induced mammary cancer: potential effects on subtypes?

Measurable tumors appeared to be more numerous in BRFs-treated animals, as an average of 3.3 ± 0.6 measurable tumors were counted at the time of sacrifice for the control group, compared to 3.6 ± 0.6 and 4.5 ± 0.8 tumors for the low and the highest doses ( Figure 1A ) but this difference failed to reach statistical significance (p > 0.05).

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Nevertheless, we noticed a higher proportion of stillborn pups from dams on either BFRs diets in comparison to the control, but this effect failed to reach significance (p = 0.4806 for control vs low dose and p = 0.1024 control vs high dose) ( Supplementary Figure 2 ).

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