Solid tumor immunotherapy using NKG2D-based adaptor CAR T cells.

Cell Rep Med · 2024 · PMC11604534 · PMID 39566469

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NKG2D/Dap10-12 CAR T cells enrich in culture due to fratricide Following expansion, NKG2D/Dap10-12 cells showed a trend toward elevated LAG-3 and Tim-3 expression, although CD69 and PD1 levels remained similar to controls ( Figures S2 A and S2B).

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