The potentiator Ivacaftor given to pwCF with the G551D mutation decreased AA and also showed a trend to less prostanoid excretion, 392 but hitherto studies in pwCF have not shown influence on the classical plasma fatty acid pattern by the new modulators, 69 , 71 despite that several studies have shown a general influence on PC and ceramides. 40 , 41 , 42 , 43 , 44 , 155 , 393 Possible mechanisms o
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