Barely Significant
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Presence of patent foramen ovale does not increase cerebrovascular event rates in patients with atrial fibrillation following left atrial appendage closure.

Heliyon · 2024 · PMC11609229 · PMID 39624313

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However, after excluding systemic embolism and TIA, the differences in all-cause ischemic stroke did not reach statistical significance, which is consistent with our data.

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