showed a trendp = 0.0598
CCL2 (MCP-1) also showed a trend towards elevated levels in E0771 mice receiving carbo/pax treatment when compared to anti-PD-1-treated mice ( p = 0.0598) and IgG controls ( p = 0.0567) (Fig. 9 B).
CCL2 (MCP-1) also showed a trend towards elevated levels in E0771 mice receiving carbo/pax treatment when compared to anti-PD-1-treated mice ( p = 0.0598) and IgG controls ( p = 0.0567) (Fig. 9 B).
This finding suggests that both canonical and noncanonical NF-κB signaling is involved in response to anti-PD-1 therapy, and that there may be significant interplay between these two pathways.