The novel estrogen receptor beta agonist EGX358 and <i>APOE</i> genotype influence memory, vasomotor, and anxiety outcomes in an Alzheimer's mouse model.

Although mice of this age are still considered young adults, amyloid accumulation in EFAD mice is already striking by 4 months of age and quite significant by 6 months of age ( Youmans et al., 2012 ; Tai et al., 2017 ).

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