Although the reductions observed in these individual subsets did not reach statistical significance, the overall DC population derived from Nfatc1 fl/fl x Cd11cCre mice treated with HDM exhibited a statistically significant decrease ( Fig 2 , H-J ).
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NFATc1 in CD4<sup>+</sup> T cells and CD11c<sup>+</sup> dendritic cells drives T<sub>H</sub>2-mediated eosinophilic inflammation in allergic asthma.
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